Pharmacokinetics and Pharmacodynamics of Common Pediatric Medications

Abstract

Pharmacokinetics (PK) and pharmacodynamics (PD) are crucial in understanding drug action, especially in pediatric populations where physiological differences significantly impact drug metabolism and response. This paper explores the PK and PD of commonly prescribed pediatric medications, providing a comprehensive analysis from absorption to excretion and the drug-receptor interactions. Emphasis is placed on the unique challenges in pediatric pharmacotherapy and the importance of tailoring drug regimens to pediatric patients. Key findings indicate significant variability in drug absorption, distribution, metabolism, and excretion across different pediatric age groups, necessitating careful consideration of age-specific dosing and therapeutic monitoring to ensure safety and efficacy. This study underscores the need for ongoing research to better understand pediatric pharmacology and improve clinical outcomes.